Kotani K

• The Importance of the Harmonization and Standardization of Lipoprotein(a) Measurements 2025-02-19
  No abstract
  Kazuhiko Kotani
• Retention of locally injected human iPS cell-derived cardiomyocytes into the myocardium using hydrolyzed gelatin 2025-02-07
  This study explored the impact of hydrolyzed gelatin (HG) concentration on the retention and therapeutic efficacy of human iPS cell-derived cardiomyocytes (hiPSC-CMs) when injected into the myocardium. The solubility of HG allows precise control over its concentration, influencing the distribution and leakage of injected solutions, which may affect therapeutic outcomes. Using both ex vivo and […]
  Jun Iida
• Laparoscopic repair combined with hysteroscopy of cesarean section scar after cesarean scar pregnancy resulting in a live birth: A case report 2025-02-03
  We report a case where a spontaneous pregnancy and delivery of a live baby were achieved after laparoscopic repair combined with hysteroscopy of the cesarean section scar secondary to treatment for a prior cesarian section scar pregnancy. [Case] 31 years old, three pregnancies, and one delivery. A spontaneous abortion. Her first child was delivered by […]
  Kyohei Takada
• Integrating Patient-Generated Health Data from Mobile Devices into Electronic Health Records: Best Practice Recommendations by the IFCC Committee on Mobile Health and Bioengineering in Laboratory Medicine (C-MHBLM) 2025-01-15
  CONCLUSIONS: Considerations for interface ease-of-use, display of patient data in the EHR/EMR, and needs-based training programs for healthcare staff to understand the critical requirements, proper use, and integration of mobile health devices with EHR/EMRs are provided. Cooperation between healthcare providers, device manufacturers, and software developers is also recommended to drive future innovation in mobile health […]
  James H Nichols
• Telemedicine for diseases between primary care physicians on remote islands and specialists in mainland in Japan: a questionnaire survey 2025-01-09
  CONCLUSION: These data may be useful for the future development of telemedicine involving primary care physicians on remote islands and mainland specialists.
  Miki Yamauchi
• The importance of using interdental cleaning devices on prevention of tooth loss in an employee population: a cross-sectional study 2024-12-20
  CONCLUSION: A longer-term use of interdental cleaning devices could improve oral health outcomes in this population, while the impact could differ depending on the basis of periodontal status. These findings would be useful for making strategies for oral health promotion in healthier people as employees.
  Kyoko Nakao
• Chemical and Heat Treatment for Viral Inactivation in Porcine-Derived Gelatin 2024-12-05
  CONCLUSION: The chemical and heat treatment steps exhibited meaningful viral inactivation capacity. They are integrated parts in the extraction and manufacturing process of porcine-derived gelatin, ensuring virus safety for use in medical applications.
  Francois Marie Ngako Kadji
• Aspirin-Exacerbated Respiratory Disease Complicated by Eosinophilic Esophagitis: A Case Report 2024-11-26
  A 59-year-old woman developed sudden dyspnea after taking non-steroidal anti-inflammatory drugs (NSAIDs) for epigastralgia. She had a history of bronchial asthma after childbirth. Computed tomography showed bilateral peripheral bronchial wall thickening, lumen narrowing, obstruction, and circumferential lower esophageal mucosal edema. The patient was diagnosed with aspirin-exacerbated respiratory disease (AERD), a hypersensitivity reaction. Respiratory symptoms improved […]
  Eiichi Kakehi
• <em>Communication:</em> 4-Hydroxynonenal and Fracture Risk in the Community-Dwelling Older People 2024-11-13
  CONCLUSIONS: 4-HNE was suggested to be positively associated with fracture risk. This molecule may be a clinical candidate oxidative stress marker for fracture risk in the older population.
  Nayuta Shimizu
• Revealing single-neuron and network-activity interaction by combining high-density microelectrode array and optogenetics 2024-11-11
  The synchronous activity of neuronal networks is considered crucial for brain function. However, the interaction between single-neuron activity and network-wide activity remains poorly understood. This study explored this interaction within cultured networks of rat cortical neurons. Employing a combination of high-density microelectrode array recording and optogenetic stimulation, we established an experimental setup enabling simultaneous recording […]
  Toki Kobayashi
• Nonalcoholic Fatty Liver Disease Risk and Proprotein Convertase Subtilisin Kexin 9 in Familial Hypercholesterolemia Under Statin Treatment 2024-11-09
  CONCLUSIONS: Their negative correlation might give a hypothetical insight into the effect of statin treatment on the development of NAFLD, in relation to PCSK9 behavior, in patients with FH.
  Masato Hamasaki
• Predictors of Immediate Deterioration of the Child-Pugh Classification From A to B After Transcatheter Arterial Chemo-Embolization for Treatment-Naive Hepatocellular Carcinoma 2024-11-02
  CONCLUSIONS: A combination of serum albumin ≤ 3.8 g/dL, PT ≤ 80%, and largest tumor diameter ≥ 3.8 cm can predict the immediate deterioration of the Child-Pugh classification from A to B following TACE.
  Kazuo Asano
• Analyzing top-down visual attention in the context of gamma oscillations: a layer- dependent network-of- networks approach 2024-10-08
  Top-down visual attention is a fundamental cognitive process that allows individuals to selectively attend to salient visual stimuli in the environment. Recent empirical findings have revealed that gamma oscillations participate in the modulation of visual attention. However, computational studies face challenges when analyzing the attentional process in the context of gamma oscillation due to the […]
  Tianyi Zheng
• Dispatch of replacement doctors from core hospitals to rural clinics in Japan 2024-10-02
  CONCLUSION: More studies are warranted regarding the number of doctors and their functions in core hospitals to ensure DRD.
  Kazuhiko Kotani
• Physician retention and migration in rural clinics designated for areas without physicians in Japan: descriptive epidemiological study using the national physicians' survey 2024-09-11
  CONCLUSIONS: Many migrating physicians choose to work at hospitals after migrating from RCDAs. It was seemed that the physician dispatch system between RCDA and CHRA has been a measure to secure physicians in rural areas. Young age, obtaining board certification, and changes in areas of practice were associated with physician migration from RCDAs.
  Hiroyuki Teraura