African swine fever (ASF) is considered as one of the most threatening diseases for the pig farming industry all over the world. Due to the lack of an effective vaccine, organized farms and backyard rearing must strictly enforce control measures in order to combat the disease. The present report describes the ASF epidemic in a […]
Hagenia abyssinica (HA) is a monotypic tree species used as traditional medicine against various diseases and conditions in African countries. HA is also a multipurpose plant used for furniture, fuel wood, soil fertility management, and rainwater conservation, along with medicinal usage. In different in vitro, in vivo, ex vivo, and human studies, the potential of […]
CONCLUSIONS: This study highlights the need for public health policies focused on preventing obesity, promoting physical activity, and improving healthcare access. It also calls for addressing regional disparities in T2DM prevalence and mortality to better allocate resources and prioritize policies to combat the diabetes epidemic inSouth Asia.
Resistance to shattering is essential for seed production in domesticated crops. In a recent study, Li et al. found that this trait arose in soybean through mutations in two genes, Shattering1 (Sh1) and Pod dehiscence1 (Pdh1), within a single quantitative trait locus (QTL). Sh1 reduces fiber cap cell wall thickness, while Pdh1 regulates lignin distribution. […]
Recent research has underscored the pivotal role of chronic inflammation in cancer development. Investigations have elucidated key molecular mechanisms underpinning inflammation-related cancer. Extrinsic pathway, driven by inflammatory conditions and intrinsic pathway, propelled by genetic events, emerged as critical links between inflammation and carcinogenesis. The persistent inflammation exacerbates genomic instability, providing a mechanistic link between inflammation […]
CONCLUSION: Impella significantly reduces 6-month all-cause mortality in patients with CS following AMI compared to standard of care. However, this survival benefit is offset by a substantial increase in major bleeding, limb ischemia, and sepsis risks associated with Impella. Future large scale trials are needed to validate these findings and refine clinical guidelines for the […]
CONCLUSION: These findings suggest that GCM patients have high risk of mortality and lower risk of HF, VT, AV node block, and AF when compared with CS.
CONCLUSIONS: Our findings provide a comprehensive understanding of the evolution and expansion of IRE1 genes in different plant species. These findings provide a foundation for further in-depth research on the functional diversity of IREs in nutritious crops following polyploidization. By linking the UPR with HSR, IRE1 could be a key contributor to wheat's resilience against […]
CONCLUSION: Marathi Version of the patient asthma knowledge questionnaire (PAKQ) is cross-culturally adapted and reliable; it will prove to be a beneficial tool to assess the disease-specific knowledge of bronchial asthma.
CONCLUSION: Colchicine was associated with an overall reduction in the risk of incidence of ACE and MI; however, no such effect was observed with mortality and stroke.
Regular exercise as part of one's lifestyle is well-recognized for its beneficial effect on several diseases such as cardiovascular disease and obesity; however, many questions remain unanswered regarding the effects of exercise on the gut environment. This study aimed to investigate the impact of long-term endurance exercise on modulating inflammation and endoplasmic reticulum (ER) stress. […]
CONCLUSION: Interscalene nerve block combined with suprascapular nerve block should be considered an alternative approach to general anesthesia for shoulder surgeries. Thus sole regional anesthesia can be considered a novel approach for all types of shoulder surgeries and is significantly safer for ASA Grade III and IV patients.
CONCLUSION: Frequency of TCFA, microchannels, macrophages, and intimal thickness was significantly higher in older ACS patients compared with very young patients. However, fibrous cap thickness was significantly greater in very young ACS patients compared with older patients.
Jaiswal V