Rehabilitation of transfemoral amputees remains a societal challenge due to the absence of natural knee joint motion. Despite progress in high-end prosthetic knee joints, issues of affordability, functionality, and patient-specific fitting persist. This study addresses these concerns through an indigenously developed, patient-specific configurable polycentric knee joint with improved functionalities. Five transfemoral amputees and ten healthy […]
CONCLUSION: Despite initial declines, recent trends indicate a resurgence in atherosclerosis-related mortality among diabetic patients, particularly in specific racial groups, rural areas, and certain regions. These findings underscore the need for targeted interventions to address disparities and improve cardiovascular outcomes in diabetic populations.
CONCLUSION: No significant difference was demonstrated between the 2 strategies in the short-term outcomes. However, long-term outcomes in the MV-PCI group were superior to culprit vessel percutaneous coronary intervention in non-ST elevation myocardial infarction patients with multivessel disease. Long-term outcomes included mortality, repeat revascularization, stent thrombosis, and MI. However, randomized controlled trials are needed to […]
BACKGROUND: Injuries are among the top causes of mortality and disability in southeast Asia. Although injury prevention is a key health priority in the Post-2015 Health Development Agenda of the Association of Southeast Asian Nations (ASEAN), the focus was placed solely on road injuries. The absence of a broader recognition of injury burden and trends […]
Secondary prevention after acute coronary syndromes is the key strategy to reduce the residual cardiovascular disease risk. A tailored assessment is necessary to suggest the best management and treatment for patients. Sex and gender differences should be strongly considered during cardiovascular evaluation and risk estimation. Indeed, women have a worse outcome than men and are […]
CONCLUSION: The burden of diabetes in India has risen markedly over the past three decades. These findings underscore the urgent need for health policies that emphasize lifestyle modifications and improved healthcare access. A comprehensive approach that integrates primary prevention through community-based health education, dietary counseling, and initiatives to promote physical activity with secondary prevention measures […]
Non-traditional cardiovascular risk factors (RFs) are increasingly emerging as important modifiers of cardiovascular risk (CVR), offering insights beyond traditional metrics like hypertension, diabetes, and dyslipidemia. These include novel biomarkers, chronic conditions (e.g., chronic kidney disease and chronic obstructive pulmonary disease), environmental exposures, chronic inflammation, infections, psychosocial factors, and sex-specific conditions, all of which influence the […]
A set of phosphine-free Ru(II)-CNC pincer complexes with benzimidazolylidene-based CNC-ligands have been synthesized and characterized which show excellent catalytic activity towards α-alkylation of ketones using primary alcohols. DFT investigations revealed that these seemingly non-bifunctional complexes can operate via inner-sphere and outer-sphere mechanisms for the alcohol dehydrogenation step; however, the outer-sphere path is favored for the […]
India is the tenth most polluted nation in the world, according to the World Health Organization (WHO) 2022 assessment. Approximately 1.67 million deaths are caused by lung, cardiovascular, stroke, and chronic pulmonary obstruction worldwide (WHO 2024). In 2019, 1.36% of GDP was reported to be lost because of air pollution and related issues. The results […]
Loss of skeletal muscle mass and strength can result from various factors, including malnutrition, glucocorticoid usage, and diseases. The mealworm (Tenebrio molitor larvae) is an edible insect gaining popularity as an alternative protein-rich diet. Mealworms are expected to help alleviate muscle atrophy based on their rich, high-quality protein and peptide content, but it remains unclear […]
Systemic lupus erythematosus (SLE) is a globally prevalent autoimmune disease that affects nearly every body organ and involves multiple systems. Pericarditis is common in lupus patients, whereas cardiac tamponade is much less frequent. The occurrence of pericardial effusion and tamponade as initial symptoms is even more uncommon. Here we present a case of a 22 […]
CONCLUSIONS: TB control in GCC countries shows positive trends, reflecting successful public health interventions. However, challenges remain, particularly the high prevalence of TB among migrant populations. Continued efforts and tailored interventions are essential to sustain progress toward TB elimination.
Deep Groove Ball Bearings (DGBBs) serve multipurpose and are used for the propeller shaft movement and applications based on revolving. They have great applications in industry related to axial and radial loads. The major risk factors are faults in bearings. Data analyzed for faults in the DGBBs help us conclude that there are 4 types […]
The chronic gynecological disorder endometriosis is a debilitating condition for women's physical and psychological health. Endometriosis is a disease that causes endometrial-like tissue to grow outside the uterus and causes debilitating symptoms, including chronic pain, fatigue, and infertility. Women with endometriosis often suffer from psychological distress, especially anxiety, depression, and social isolation, which aggravates the […]
The presence of persistent organic pollutants in wastewater streams has presented significant challenges towards their removal. In the recent decade, bulk micro (1-100 μm) and nanobubble (50-150 nm) (MNB) technology has exhibited technological advancements via integration of MNB technology in degrading organic pollutants from wastewater streams. The present review critically analyses the physico-chemical properties such […]
CONCLUSION: Treatment with GLP-1 receptor agonists has beneficial effects in reducing the risk of stroke, and nonfatal stroke in patients with and without diabetes. However, no such effect was observed for fatal stroke.
CONCLUSION: Combination LLT was associated with an overall greater reduction in LDL-C, the same risk of adverse effects, and significantly lower risk of all-cause mortality, major adverse cardiovascular events, and stroke compared with statin monotherapy. Forthcoming guidelines should consider the lipid-lowering combination therapy as early as possible, preferably up-front, for more effective LDL-C goal achievement […]
The lncRNAs have deepened our understanding of crop domestication and improvement. These regulators influence key traits like yield, germination, and stress response. Future research should identify functional lncRNAs, explore their interactions, and use CRISPR for targeted improvements. Understanding their roles in polyploid crops may enhance resilience and productivity.
CONCLUSION: REs, particularly myopia, pose a significant burden among Indian schoolchildren. Despite the COVID-19 pandemic, the overall prevalence of REs has remained stable. These findings emphasize the need for continued vision screening programs and targeted interventions to reduce the prevalence of uncorrected refractive errors.
Jaiswal V